以负载Ag纳米颗粒催化的4-硝基苯酚还原（NaBH₄）作为模型反应，E. Menumerov等人通过实时光谱跟踪发现，负载Ag NPs在反应开始初期阶段就有非负载的异相Ag纳米颗粒从负载Ag纳米颗粒表面Leaching出来。即便只有亚纳米的Ag发生Leaching也会大幅提升催化活性。研究发现，Ag的Leaching与溶液中溶解的O₂有关，除去O₂后其真正活性中心变为负载的Ag纳米颗粒。

Eredzhep Menumerov, Svetlana Neretina*,et al. Identifying the True Catalyst in the Reduction of 4-Nitrophenol: A Case Study Showing the Effect of Leaching and Oxidative Etching Using Ag Catalysts

ACS Catal., 2018, 8, pp 8879–8888 DOI: 10.1021/acscatal.8b02325

https://pubs.acs.org/doi/10.1021/acscatal.8b02325#